LONGEVITY YOU CAN MEASURE
Biomarker Transformation Protocol
A clinically formulated daily protocol designed to support healthier trends across key biomarkers tied to metabolic health and longevity—by strengthening the liver’s role in lipid handling, glucose regulation, oxidative defense, and mitochondrial function. Run it consistently, then retest in 8–12 weeks to evaluate directionality and magnitude of change.
Protocol: 2 capsules daily
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Guidance from our science experts
What does Liver Health do?
Supports healthier trends in liver enzymes (ALT/AST/GGT)
Supports inflammatory tone (hs-CRP trend)
Supports lipid markers (triglycerides, LDL-C/ApoB trends)
Supports antioxidant defenses (glutathione/SOD pathways)
Supports fasting glucose and insulin response
Supports mitochondrial function and cellular energy regulation
Retest recommended at 8–12 weeks to evaluate directionality and magnitude of change.
Review Highlights
Julie R.
(5/5)
I’ve been taking Something for Liver Health for the last 5 months. My most recent blood test showed significant improvement in both my cholesterol and triglycerides (both in normal ranges which hadn’t been the case for years). I’m also noticing slow, but steady weight loss. I’m excited to continue to support my liver and so glad I found this!
Read all reviews
Good to Know
23.4 mm standard capsule length
100% plant-based, naturally sourced ingredients
Gluten free, vegan, lactose free, non-GMO, low FODMAP, sugar free, non-irradiated, sustainably sourced
No artificial colors, flavorings, or preservatives
Not recommended while pregnant, breastfeeding, or for children
Formulated in Portugal
Ingredient Technology
Indena Phytosome® Technology
This innovative system optimizes the bioavailability and pharmacokinetic profile of natural actives, allowing our body to absorb them in the best possible way.
+ Siliphos® shows up to 4x improved bioabsorption
+ Ubiqsome® shows up to 9x improved bioabsorption
Why subscribe
Biomarker transformation takes time. Clinical studies show that liver regeneration requires a minimum of six months of consistent care. Subscribing ensures you maintain a steady routine, giving your liver the time and support it needs to heal, regenerate, and thrive. Plus get:
Life-long subscription discount
20% off one-time add-ons
Free gift with 3rd order
Exclusive access to our team of experts
Supplement Facts
Track the markers that move first.
A formulation framework built around liver biology, ingredient integrity, and functional outcomes. Every Biocol formula follows this standard. What changes is the biological focus. The framework does not.
Core panel (recommended):
ALT, AST, GGT (liver enzymes)
Triglycerides, LDL-C (lipid handling)
Fasting glucose + fasting insulin (insulin sensitivity; calculate HOMA-IR if desired)
hs-CRP (systemic inflammatory tone)
Optional add-ons (if you track deeper):
ApoB (atherogenic particle burden)
Ferritin (inflammatory/iron context)
VO2max (fitness metric strongly associated with long-term outcomes)
Retest at 8–12 weeks to evaluate directionality and magnitude of change.
The liver is a control point for metabolic aging.
The liver regulates core processes—lipid trafficking, glucose homeostasis, detoxification capacity, and oxidative balance. When hepatic function drifts, downstream biomarkers follow: lipids, insulin sensitivity, inflammatory tone, and energy stability.
This is not a cleanse. It is daily hepatic support designed to shift risk-relevant biomarkers over time.
Three mechanisms. One outcome: Restored biomarker homeostasis
The formula targets upstream biology that influences common labs—by supporting antioxidant defenses, mitochondrial output, and hepatic metabolic signaling.
Oxidative defense capacity
Supports glutathione activity, selenium-dependent systems, and endogenous antioxidant signaling—key to maintaining redox balance as metabolic load fluctuates.
Mitochondrial energy and cellular efficiency
Supports mitochondrial function and bioenergetics—core to cellular resilience and consistent metabolic performance over time.
Metabolic regulation (lipids + glucose handling)
Supports signaling tied to hepatic insulin sensitivity and lipid processing—including pathways commonly discussed in metabolic health research (AMPK/SIRT1-linked mechanisms).
A realistic timeline: perception first, biomarkers after.
Biomarker changes typically require consistency and time—hence the 8–12 week retest window.
Weeks 1-2
More stable digestion,
less day-to-day variability, improved consistency in energy and appetite patterns
Weeks 3–4
Improved resilience and steadier day-to-day performance
Weeks 6–8
More consistent appetite/energy regulation; fewer swings
8–12 weeks (Retest window)
Clearer movement in liver enzymes, lipid markers, glucose/insulin patterns, inflammatory tone — especially if baseline values were elevated.
Biomarker trendlines you can actually track
Expand each section to see which markers typically shift first—and what sustained improvement can look like over time.
Biological Age & General Health
Your biological age—how old your body actually functions—can be reversed by optimizing liver health. This reversal, alongside dramatic reductions in inflammation and oxidative DNA damage, means your cells age slower and function better. The result is reduced risk of age-related diseases while improving energy, mental clarity, and overall vitality.
*claims based on mono-ingredient studies
Liver Function
The liver performs over 500 essential functions daily, from detoxifying your blood to regulating metabolism and hormones. When liver enzymes normalize, it signals your liver is healing from inflammation and fat accumulation. A healthy, fat-free liver is the foundation for weight management, sustained energy, clearer skin, and protection against metabolic diseases.
*claims based on mono-ingredient studies
Performance & Resilience
Physical and mental performance depend on your body's ability to generate energy and manage stress effectively. Enhanced cardiovascular fitness combined with normalized stress hormones means better endurance, faster recovery, and improved resilience. You'll experience sustained mental sharpness and energy throughout the day, transforming how you feel and perform.
*claims based on mono-ingredient studies
Metabolic Health
Insulin resistance and blood sugar dysregulation drive type 2 diabetes, weight gain, and cardiovascular disease. Restoring insulin sensitivity and glucose control means your body regains its natural ability to manage blood sugar and burn fat efficiently. This lowers diabetes risk while making weight management effortless and sustainable.
*claims based on mono-ingredient studies
How to take
Take 2 capsules each morning on an empty stomach or before your first meal if you're intermittent fasting
The monthly program is designed for 25 days of usage plus 5 days of rest at the end of each cycle
We recommend pairing this program with a whole-food diet and a minimum of 150 minutes of exercise per week.
Clinically studied ingredients
Selected for potency and protocol compatibility.
Silybin (Siliphos®) — 100 mg
hepatocyte protection + metabolic signaling
Sulforaphane + myrosinase — 100 mg
NRF2 cellular defense + signaling
Reduced Glutathione — 100 mg
antioxidant capacity + redox balance
L-Selenomethionine (Selenium) — 169 μg
selenoprotein antioxidant systems
CoQ10 (Ubiqsome®) — 80 mg
mitochondrial energy + antioxidant function
Artichoke polyphenols — 80 mg
bile flow support + lipid metabolism pathways
Choline bitartrate (VitaCholine®) — 97 mg
lipid transport + methylation pathways
TetraSOD® microalgae — 25 mg (750 IU)
endogenous antioxidant signaling
View supplement facts
Independently tested for quality and purity
We’re committed to delivering supplements you can trust. Every batch is tested by accredited independent EU labs for safety, purity, and ingredient accuracy. Results are reviewed against strict standards, in accordance with FSSC 22000 and HACCP and in accordance with the agreed formulation and specification.
Potency of actives
Passed ✔️
We verify that each batch / formula contains the amount of actives found listed in the supplement facts.
Heavy metals
Passed ✔️
We test every product twice per year and any time there is a change in the batch of the raw material to confirm it meets international safety standards for heavy metals. As shown below. Independent lab results have consistently shown levels well within established safety limits (Below Limit of Detection = LOD).
Tested For
Result
Frequency
+ Lead
LOD
Twice Yearly
+ Lead
LOD
Twice Yearly
+ Lead
LOD
Twice Yearly
+ Lead
LOD
Twice Yearly
Based on independent laboratory testing to verify compliance with international safety limits for heavy metals. Results are representative of typical findings; individual batch data may be made available upon request.
Microbiology
Passed ✔️
All batches tested by our third party laboratory, Eurofins US, including enumeration, pathogens, and absence of harmful microorganisms.
Your questions, answered
Who is this for?
It’s for anyone aiming to enhance liver health, improve overall well-being, and optimize performance naturally. Whether you want to detox, support digestion, or feel more energized, this is for you.
What will it do to my liver?
Biomarker Transformation Protocol combines a powerhouse blend of clinically studied, nature-derived ingredients to support healthy liver enzyme levels, regular detoxification, and overall liver function.
*Ingredients like Siliphos® Silybin (our supercharged milk thistle derivative) and artichoke help to protect liver cells, stimulate bile flow, promote fat metabolism and support overall health liver function
*TetraSOD® Superoxide dismutase helps promote normal liver enzyme activity and natural liver detoxification
*Choline supports fat metabolism and prevents liver fat buildup, aiding healthy cholesterol levels
*Selenium and broccoli extract support healthy thyroid function, glucose metabolism, lung, and gut function
*Glutathione helps maintain a balances liver antioxidant state
*Ubiqsome® CoQ10 promotes normal energy levels and supports healthy cognitive function
Why is the liver so critical to all of these functions?
Your liver is a powerhouse, performing 500+ vital functions. It’s no coincidence that Liver contains the word live. The heaviest and largest organ in the body is simultaneously a storehouse, a manufacturing hub, and a processing plant.
Modern life is full of stressors that strain this core system, and so your liver is systematically reworking the food we eat into usable building blocks for our cells, neutralizing the many potentially harmful substances that we incidentally or deliberately ingest, generating a vast pharmacopeia of hormones, enzymes, clotting factors and immune molecules, controlling blood chemistry, and much more.
When will I start feeling effects?
Customers may begin feeling effects as early as the first month. However, everyone is at a different stage in their health journey, and results will vary depending on diet, exercise, consistency in taking the product daily, and other individual health factors.
We recommend a minimum of 6 months to experience the Protocol's full benefits.
Results you may expect include improved digestion, better focus and improved mood, more energy, weight loss, positive impacts on blood glucose, cholesterol, triglycerides, and liver enzymes (AST, ALT, ALP), and, over the long-term, healthier aging.
Is it compatible with my diet or dietary restrictions?
Biomarker Transformation Protocol is formulated to be gentle, safe, and widely compatible with different dietary needs. It is:
Gluten-free, dairy-free, vegan, and seafood-free
Free from yeast, dyes, sulphites, lupin, wheat, peanuts, and tree nuts
Contains no corn, artificial colors, preservatives, artificial sweeteners, or polyols
Non-irradiated, non-GMO, not animal tested
Sugar-free and calorie-free
Please note: Biomarker Transformation Protocol does contain soy. Our formula uses advanced “phytosome” technology to make plant extracts more absorbable. The phospholipids in this process are derived from soy, which is why soy is listed. Please note: this isn’t the same as eating soy protein or soy isoflavones (the compounds linked with hormonal effects) — it’s a purified component used in very small amounts to help the active botanicals work better. We always list soy clearly so anyone with allergies or sensitivities can make an informed choice.
Is it safe to take alongside other medication or supplementation?
Yes, it's completely safe to take alongside other supplements. However, if you're on prescribed medications or undergoing any treatments we always recommend you consult your doctor for personalized advice.
Is it normal if I don't start feeling better right away?
While most tolerate our liver supplements well, as your body adjusts, you may notice mild, temporary changes such as slight nausea or digestive shifts. These are common when supporting liver detoxification pathways and typically resolve as your system adapts. Because everyone responds differently, it’s best to consult your healthcare professional if any effects persist, particualrly if you are also taking prescription medications.
Can I take it if I don’t have a gallbladder?
Yes, our product works effectively even if you don’t have a gallbladder.
Do I need to change diet?
It is not necessary to change your diet to do the Biomarker Transformation Protocol. However, a balanced diet which avoids inflammatory foods like deep-fried food and refined sugars will allow for the optimization of the product. By giving the body what it needs to function, as well as toxin protection, you are allowing for a more efficient daily bodily function which is less prone to systemic stress.
Can I still drink alcohol while taking Biomarker Transformation Protocol?
Yes, you can still enjoy alcohol in moderation while taking Biomarker Transformation Protocol. If you’ve had a bigger night than usual, we recommend taking your next dose with food (for example, before your evening meal) rather than first thing in the morning on an empty stomach. This helps ensure comfortable digestion and steady support as your body recovers.
Why a 5-day break?
Your body needs a resting period to assimilate the whole-body improvements caused by the protocol's capsules. After the resting period, your organism is ready to be stimulated again, which optimizes the ingredient's efficacy.
Can I skip a month?
If you skip a month, there is no reason to worry. There is no danger in interrupting the program, although we recommend a minimum of 6 months of continuous therapy to experience the full benefits of the product.
Do you offer a money-back guarantee?
Absolutely. We offer a 90-day money-back guarantee. Don’t absolutely love Biomarker Transformation Protocol? We’ll take it back!
